Pesquisa | Biblioteca Virtual em Saúde

1.

Molecular cartography uncovers evolutionary and microenvironmental dynamics in sporadic colorectal tumors.

Heiser, Cody N; Simmons, Alan J; Revetta, Frank; McKinley, Eliot T; Ramirez-Solano, Marisol A; Wang, Jiawei; Kaur, Harsimran; Shao, Justin; Ayers, Gregory D; Wang, Yu; Glass, Sarah E; Tasneem, Naila; Chen, Zhengyi; Qin, Yan; Kim, William; Rolong, Andrea; Chen, Bob; Vega, Paige N; Drewes, Julia L; Markham, Nicholas O; Saleh, Nabil; Nikolos, Fotis; Vandekar, Simon; Jones, Angela L; Washington, M Kay; Roland, Joseph T; Chan, Keith S; Schürpf, Thomas; Sears, Cynthia L; Liu, Qi; Shrubsole, Martha J; Coffey, Robert J; Lau, Ken S.

Cell ; 186(25): 5620-5637.e16, 2023 12 07.

Artigo em Inglês | MEDLINE | ID: mdl-38065082

2.

Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps.

Chen, Bob; Scurrah, Cherie' R; McKinley, Eliot T; Simmons, Alan J; Ramirez-Solano, Marisol A; Zhu, Xiangzhu; Markham, Nicholas O; Heiser, Cody N; Vega, Paige N; Rolong, Andrea; Kim, Hyeyon; Sheng, Quanhu; Drewes, Julia L; Zhou, Yuan; Southard-Smith, Austin N; Xu, Yanwen; Ro, James; Jones, Angela L; Revetta, Frank; Berry, Lynne D; Niitsu, Hiroaki; Islam, Mirazul; Pelka, Karin; Hofree, Matan; Chen, Jonathan H; Sarkizova, Siranush; Ng, Kimmie; Giannakis, Marios; Boland, Genevieve M; Aguirre, Andrew J; Anderson, Ana C; Rozenblatt-Rosen, Orit; Regev, Aviv; Hacohen, Nir; Kawasaki, Kenta; Sato, Toshiro; Goettel, Jeremy A; Grady, William M; Zheng, Wei; Washington, M Kay; Cai, Qiuyin; Sears, Cynthia L; Goldenring, James R; Franklin, Jeffrey L; Su, Timothy; Huh, Won Jae; Vandekar, Simon; Roland, Joseph T; Liu, Qi; Coffey, Robert J.

Cell ; 184(26): 6262-6280.e26, 2021 12 22.

Artigo em Inglês | MEDLINE | ID: mdl-34910928

3.

Reassessment of Exosome Composition.

Jeppesen, Dennis K; Fenix, Aidan M; Franklin, Jeffrey L; Higginbotham, James N; Zhang, Qin; Zimmerman, Lisa J; Liebler, Daniel C; Ping, Jie; Liu, Qi; Evans, Rachel; Fissell, William H; Patton, James G; Rome, Leonard H; Burnette, Dylan T; Coffey, Robert J.

Cell ; 177(2): 428-445.e18, 2019 04 04.

Artigo em Inglês | MEDLINE | ID: mdl-30951670

4.

Human SMARCA5 is continuously required to maintain nucleosome spacing.

Bomber, Monica L; Wang, Jing; Liu, Qi; Barnett, Kelly R; Layden, Hillary M; Hodges, Emily; Stengel, Kristy R; Hiebert, Scott W.

Mol Cell ; 83(4): 507-522.e6, 2023 02 16.

Artigo em Inglês | MEDLINE | ID: mdl-36630954

5.

PAX3-FOXO1 coordinates enhancer architecture, eRNA transcription, and RNA polymerase pause release at select gene targets.

Zhang, Susu; Wang, Jing; Liu, Qi; McDonald, W Hayes; Bomber, Monica L; Layden, Hillary M; Ellis, Jacob; Borinstein, Scott C; Hiebert, Scott W; Stengel, Kristy R.

Mol Cell ; 82(23): 4428-4442.e7, 2022 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-36395771

6.

A pan-cancer transcriptome analysis of exitron splicing identifies novel cancer driver genes and neoepitopes.

Wang, Ting-You; Liu, Qi; Ren, Yanan; Alam, Sk Kayum; Wang, Li; Zhu, Zhu; Hoeppner, Luke H; Dehm, Scott M; Cao, Qi; Yang, Rendong.

Mol Cell ; 81(10): 2246-2260.e12, 2021 05 20.

Artigo em Inglês | MEDLINE | ID: mdl-33861991

7.

METTL1-mediated m⁷G modification of Arg-TCT tRNA drives oncogenic transformation.

Orellana, Esteban A; Liu, Qi; Yankova, Eliza; Pirouz, Mehdi; De Braekeleer, Etienne; Zhang, Wencai; Lim, Jihoon; Aspris, Demetrios; Sendinc, Erdem; Garyfallos, Dimitrios A; Gu, Muxin; Ali, Raja; Gutierrez, Alejandro; Mikutis, Sigitas; Bernardes, Gonçalo J L; Fischer, Eric S; Bradley, Allan; Vassiliou, George S; Slack, Frank J; Tzelepis, Konstantinos; Gregory, Richard I.

Mol Cell ; 81(16): 3323-3338.e14, 2021 08 19.

Artigo em Inglês | MEDLINE | ID: mdl-34352207

8.

In vivo single-molecule analysis reveals COOLAIR RNA structural diversity.

Yang, Minglei; Zhu, Pan; Cheema, Jitender; Bloomer, Rebecca; Mikulski, Pawel; Liu, Qi; Zhang, Yueying; Dean, Caroline; Ding, Yiliang.

Nature ; 609(7926): 394-399, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-35978193

9.

CYCLOIDEA-like genes control floral symmetry, floral orientation, and nectar guide patterning.

Yang, Xia; Wang, Yang; Liu, Tian-Xia; Liu, Qi; Liu, Jing; Lü, Tian-Feng; Yang, Rui-Xue; Guo, Feng-Xian; Wang, Yin-Zheng.

Plant Cell ; 35(8): 2799-2820, 2023 08 02.

Artigo em Inglês | MEDLINE | ID: mdl-37132634

10.

Clinical targeting of HIV capsid protein with a long-acting small molecule.

Link, John O; Rhee, Martin S; Tse, Winston C; Zheng, Jim; Somoza, John R; Rowe, William; Begley, Rebecca; Chiu, Anna; Mulato, Andrew; Hansen, Derek; Singer, Eric; Tsai, Luong K; Bam, Rujuta A; Chou, Chien-Hung; Canales, Eda; Brizgys, Gediminas; Zhang, Jennifer R; Li, Jiayao; Graupe, Michael; Morganelli, Philip; Liu, Qi; Wu, Qiaoyin; Halcomb, Randall L; Saito, Roland D; Schroeder, Scott D; Lazerwith, Scott E; Bondy, Steven; Jin, Debi; Hung, Magdeleine; Novikov, Nikolai; Liu, Xiaohong; Villaseñor, Armando G; Cannizzaro, Carina E; Hu, Eric Y; Anderson, Robert L; Appleby, Todd C; Lu, Bing; Mwangi, Judy; Liclican, Albert; Niedziela-Majka, Anita; Papalia, Giuseppe A; Wong, Melanie H; Leavitt, Stephanie A; Xu, Yili; Koditek, David; Stepan, George J; Yu, Helen; Pagratis, Nikos; Clancy, Sheila; Ahmadyar, Shekeba.

Nature ; 584(7822): 614-618, 2020 08.

Artigo em Inglês | MEDLINE | ID: mdl-32612233

11.

Mettl1/Wdr4-Mediated m⁷G tRNA Methylome Is Required for Normal mRNA Translation and Embryonic Stem Cell Self-Renewal and Differentiation.

Lin, Shuibin; Liu, Qi; Lelyveld, Victor S; Choe, Junho; Szostak, Jack W; Gregory, Richard I.

Mol Cell ; 71(2): 244-255.e5, 2018 07 19.

Artigo em Inglês | MEDLINE | ID: mdl-29983320

12.

PRMD: an integrated database for plant RNA modifications.

Lang, Xiaoqiang; Yu, Chunyan; Shen, Mengyuan; Gu, Lei; Qian, Qian; Zhou, Degui; Tan, Jiantao; Li, Yiliang; Peng, Xin; Diao, Shu; Deng, Zhujun; Ruan, Zhaohui; Xu, Zhi; Xing, Junlian; Li, Chen; Wang, Runfeng; Ding, Changjun; Cao, Yi; Liu, Qi.

Nucleic Acids Res ; 52(D1): D1597-D1613, 2024 Jan 05.

Artigo em Inglês | MEDLINE | ID: mdl-37831097

13.

Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models.

Teuscher, Kevin B; Chowdhury, Somenath; Meyers, Kenneth M; Tian, Jianhua; Sai, Jiqing; Van Meveren, Mayme; South, Taylor M; Sensintaffar, John L; Rietz, Tyson A; Goswami, Soumita; Wang, Jing; Grieb, Brian C; Lorey, Shelly L; Howard, Gregory C; Liu, Qi; Moore, William J; Stott, Gordon M; Tansey, William P; Lee, Taekyu; Fesik, Stephen W.

Proc Natl Acad Sci U S A ; 120(1): e2211297120, 2023 01 03.

Artigo em Inglês | MEDLINE | ID: mdl-36574664

14.

BRD9-SMAD2/3 Orchestrates Stemness and Tumorigenesis in Pancreatic Ductal Adenocarcinoma.

Feng, Yuliang; Cai, Liuyang; Pook, Martin; Liu, Feng; Chang, Chao-Hui; Mouti, Mai Abdel; Nibhani, Reshma; Militi, Stefania; Dunford, James; Philpott, Martin; Fan, Yanbo; Fan, Guo-Chang; Liu, Qi; Qi, Jun; Wang, Cheng; Hong, Wanzi; Morgan, Hannah; Wang, Mingyang; Sadayappan, Sakthivel; Jegga, Anil G; Oppermann, Udo; Wang, Yigang; Huang, Wei; Jiang, Lei; Pauklin, Siim.

Gastroenterology ; 166(1): 139-154, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-37739089

15.

Scalable and model-free detection of spatial patterns and colocalization.

Liu, Qi; Hsu, Chih-Yuan; Shyr, Yu.

Genome Res ; 32(9): 1736-1745, 2022 09.

Artigo em Inglês | MEDLINE | ID: mdl-36223499

16.

Multi-task bioassay pre-training for protein-ligand binding affinity prediction.

Yan, Jiaxian; Ye, Zhaofeng; Yang, Ziyi; Lu, Chengqiang; Zhang, Shengyu; Liu, Qi; Qiu, Jiezhong.

Brief Bioinform ; 25(1)2023 11 22.

Artigo em Inglês | MEDLINE | ID: mdl-38084920

17.

scKWARN: Kernel-weighted-average robust normalization for single-cell RNA-seq data.

Hsu, Chih-Yuan; Chang, Chia-Jung; Liu, Qi; Shyr, Yu.

Bioinformatics ; 40(2)2024 02 01.

Artigo em Inglês | MEDLINE | ID: mdl-38237908

18.

Ferroptosis Contributes to Microvascular Dysfunction in Diabetic Retinopathy.

Liu, Qun; Liu, Chao-Qun; Yi, Wan-Zhao; Ouyang, Pei-Wen; Yang, Bo-Fan; Liu, Qi; Liu, Jing-Min; Wu, Ya-Ni; Liang, Ai-Rong; Cui, Yu-Hong; Meng, Jing; Li, Xiu-Yun; Pan, Hong-Wei.

Am J Pathol ; 2024 Feb 28.

Artigo em Inglês | MEDLINE | ID: mdl-38417697

19.

Multiomics identifies metabolic subtypes based on fatty acid degradation allocating personalized treatment in hepatocellular carcinoma.

Li, Binghua; Li, Yunzheng; Zhou, Huajun; Xu, Yanchao; Cao, Yajuan; Cheng, Chunxiao; Peng, Jin; Li, Huan; Zhang, Laizhu; Su, Ke; Xu, Zhu; Hu, Yue; Lu, Jiaming; Lu, Yijun; Qian, Liyuan; Wang, Ye; Zhang, Yuchen; Liu, Qi; Xie, Yuanyuan; Guo, Sheng; Mehal, Wajahat Z; Yu, Decai.

Hepatology ; 79(2): 289-306, 2024 Feb 01.

Artigo em Inglês | MEDLINE | ID: mdl-37540187

20.

Exosomes in tumor-stroma crosstalk: Shaping the immune microenvironment in colorectal cancer.

Zhang, Yawei; Huo, Mingyu; Li, Wenchao; Zhang, Hongyu; Liu, Qi; Jiang, Jianwu; Fu, Yang; Huang, Changjun.

FASEB J ; 38(6): e23548, 2024 Mar 31.

Artigo em Inglês | MEDLINE | ID: mdl-38491832

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